NorthStar Solutions - Innovative Mo-99 Production

Introducing NorthStar's Mo-99 Production Process


NorthStar believes that recent FDA Approval of the RadioGenix® System and non-uranium based Mo-99 production technology will mark a new era in nuclear medicine technology by providing a reliable, domestically produced and environmentally friendly Mo-99/Tc-99m supply for the United States.

NorthStar believes that recent FDA Approval of the RadioGenix® System (technetium Tc 99m generator) and non-uranium based Mo-99 production technology will mark a new era in nuclear medicine technology by providing a reliable, domestically produced and environmentally friendly Mo-99/Tc-99m supply for the United States.

Recently approved by the U.S. Food and Drug Administration (FDA), non-uranium based processes for the production of Mo-99 are based on proven and well-established principles, yet mark a significant advancement in current technology.  By utilizing state-of-the-art chemical processing to achieve domestic Mo-99 production without the use of any uranium target material, NorthStar’s product meets all appropriate Pharmacopeia standards for Mo-99.

NorthStar uses naturally occurring Molybdenum (nMo) as its starting material.  It is found in the earth’s crust as molybdenite, commonly used for manufacturing high strength alloy steel.  About 24% of naturally occurring nMo is the useful and stable Mo-98 isotope.  When small discs (called “targets”) are placed in a reactor’s “neutron flux trap”, the Mo-98 captures a “spare” neutron and becomes the medically useful Mo-99 isotope.

A simple, modern, chemical processing technique is used to dissolve the nMo targets.  The resulting radioactive solution is then filled into our Source Vessels shielded with tungsten and shipped to radiopharmacies across the United States.

Upon arrival at the radiopharmacy, the Source Vessels are mounted into the RadioGenix® System, in order to extract Technetium-99m (Tc-99m) from our Mo-99 source. Tc-99m is then used for medical imaging studies.

Only use potassium molybdate Mo-99, processing reagents, saline and other components supplied by NorthStar Medical Radioisotopes.

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