NorthStar’s facilities in Wisconsin house our Company Headquarters and production, R&D and manufacturing, as well as all of our other departments.

Company Headquarters and
Primary Manufacturing Locations

Beloit, WI

Corporate Headquarters

1800 Gateway Boulevard, Beloit, WI 53511

NorthStar’s corporate headquarters in Beloit house our executive, administrative, Quality Affairs/Regulatory Affairs, logistics and Copper-67 (Cu-67) production activities, customer care, and training teams.

Isotope Processing Facility

1800 Gateway Boulevard, Beloit, WI 53511

This 20,000 sq ft facility was completed in September 2019, features our chemical processing line and is currently producing Copper-67 (Cu-67) in limited quantities. NorthStar is investing to upscale this process and equipment for large commercial quantities. In addition, this facility includes our analytical testing laboratory and additional hot cells for future isotope processing.

Copper-67 Accelerator Production Facility

1800 Gateway Boulevard, Beloit, WI 53511

Ground breaking for this 30,000 sq ft facility was celebrated in September 2019. The first pair of electron beam accelerators are operational.

NorthStar’s unique and proprietary electron accelerator production facility and processes are designed to provide efficiencies throughout the production process, thereby enabling the production of multiple radioisotopes utilizing the same equipment. With this in mind, we are now routinely producing Cu-67.

Up to three additional mirror-image accelerator facilities are planned to support increased market demand for Cu-67, and other radioisotopes.

Sept 2019
Accelerator Production facility groundbreaking
Jan 2021
Facility construction completed
Apr 2021
Delivery of electron accelerator pair
Mid 2022
Electron accelerator pair and associated equipment operational
Mid 2023
Initial production of radiochemical grade Cu-67


1800 Gateway Boulevard, Beloit, WI 53511

Groundbreaking for this 30,000+ sq ft first-of-its-kind Actinium-225 (Ac-225) Production facility, dedicated exclusively to commercial-scale production of non-carrier added (n.c.a.) Ac-225, was celebrated in September 2021. The facility houses a Rhodotron® TT300 HE electron beam accelerator used solely for the production of Ac-225. This marks the third electron accelerator NorthStar has purchased from IBA. Utilizing design concepts and key learnings from our Mo-99 and Cu-67 programs, this facility will allow for more efficient and expedited completion timelines, with potential future expansion plans in mind.

Construction began in early 2022 with initial production of radiochemical grade Ac-225 planned for 2024. We expect submission of the Drug Master File to the U.S. Food and Drug Administration (U.S. FDA) in 2025.

Sept 2021
Facility Groundbreaking
Nov 2021
Orders placed for accelerators and essential long-lead items
Early 2022
Construction begins
Q3 2024
Initial production of radiochemical grade Ac-225
Q2 2025
Drug Master File Submitted to FDA


1800 Gateway Boulevard, Beloit, WI 53511

NorthStar Medical Radioisotopes will be the first and only U.S. company housing world class, commercial-scale, multi-radioisotope production and radiopharmaceutical development services on one campus. Our new Radiopharmaceutical CDMO facility is located on our 55-acre campus in Beloit, Wisconsin, enabling collaborator companies to realize the logistical, regulatory and other efficiency benefits afforded by a single site location.

Groundbreaking for the new 52,000 sq ft, state-of-the-art Radiopharmaceutical CDMO facility occurred in November 2022. The facility is purpose-engineered to meet growing demands for therapeutic and diagnostic radiopharmaceuticals. Also designed with the needs of our partner companies in mind, the facility will offer the flexibility needed to support advancement of their products, from development to commercialization.

Oct 2022
Facility Groundbreaking
Early 2023
Construction begins
June 2024
Construction complete
Jan 2025
CDMO/CMO Production Operations Launch

Additional Facilities

1800 Gateway Boulevard, Beloit, WI 53511

NorthStar’s 55-acre Beloit campus has space for additional facilities that will support the production of other isotopes and related products as their development progresses.

Madison, WI

Research and Development

5249 Femrite Drive, Madison, WI 53718

Femrite Drive is our 10,000 ft2 facility that is the Research and Development center of expertise for our product development engineering, microbiology and science teams. This facility also houses state-of-the-art microbiology and radiochemistry laboratories to support analytical and product testing.

Research and Development

3060 Progress Road, Madison, WI 53716

Progress Road is a 10,000 ft2 facility that is the Research and Development center of expertise for our isotope production equipment and includes our process development engineering, material testing and chemistry development teams. This facility also houses state-of-the-art equipment for developing, testing and upgrading our novel isotope processing equipment.